Incubator T

Incubator T

Multicolor imaging with total internal reflection fluorescence (TIRF) microscope

Super-photostable organic dye for long-term live-cell single-protein imaging.

Nature Methods, January 2025

Reference
https://www.nature.com/articles/s41592-024-02584-0

Cholesterol crystals imaging on lipid droplet

Lipid Droplet Surface Promotes 3D Morphological Evolution of Non-Rhomboidal
Cholesterol Crystals.

Advanced Science, January 2025

Reference
https://advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202409201

Organoid(hAGO) live imaging

Helicobacter pylori VacA-induced mitochondrial damage in the gastric pit
cells of the antrum and therapeutic rescue.

Biomaterials, March 2025

Reference
https://www.sciencedirect.com/science/article/pii/S0142961224003764?via%3Dihub

Live imaging of primary cortical neurons

Brain microenvironment-remodeling nanomedicine improves cerebral glucose metabolism,
mitochondrial activity and synaptic function in a mouse model of Alzheimer’s disease.

Biomaterials, July 2025

Reference
https://www.sciencedirect.com/science/article/pii/S0142961225000614?via%3Dihub

Live-cell calcium Imaging(Primary cortical astrocytes)

Optogenetic calcium modulation in astrocytes enhances post-stroke recovery in
chronic capsular infarct.

Science Advances, January 2025

Reference
https://www.science.org/doi/10.1126/sciadv.adn7577

Cellular migration tracking

Hepatocyte TM4SF5-mediated cytosolic NCOA3 stabilization and macropinocytosis
support albumin uptake and bioenergetics for hepatocellular carcinoma progression.

Experimental & Molecular Medicine, April 2025

Reference
https://www.nature.com/articles/s12276-025-01438-9

Epi-fluorescence imaging

Glutamylation of centrosomes ensures their function by recruiting microtubule
nucleation factors.

The EMBO Journal, April 2025

Reference
https://www.embopress.org/doi/full/10.1038/s44318-025-00435-y

Real-Time Live Cell Imaging(Bacterial proliferation)

Probiotic Antimicrobial Evaluation Via Real-Time Profiling of Bacterial Cell
Proliferation Using Stochastic Kinetics.

ACS Sensors, February 2025

Reference
https://pubs.acs.org/doi/10.1021/acssensors.4c03003

Cell viability (Caspase activation)

CRISPR-array-mediated imaging of non-repetitive and multiplex genomic loci in living cells.

nature methods, July 2024

Reference
https://www.nature.com/articles/s41592-024-02333-3

Confocal Live-Cell Imaging (Synapses Imaging)

Real-time visualization of structural dynamics of synapses in live cells in vivo.

nature methods, January 2024

Reference
https://www.nature.com/articles/s41592-023-02122-4

Nanotopographic Time Lapse Imaging

Engineered Nanotopographies Induce Transient Openings in the Nuclear Membrane.

Advanced Functional Materials, September 2024

Reference
https://doi.org/10.1002/adfm.202410035

UV-A laser micro-irradiation (DNA double-strand break)

The Fanconi anemia core complex promotes CtIP-dependent end resection to drive
homologous recombination at DNA doublestrand breaks.

nature communications, August 2024

Reference
https://www.nature.com/articles/s41467-024-51090-6

Live cell single-molecule imaging

Optogenetic control of mRNA condensation reveals an intimate link
between condensate material properties and functions.

nature communications, April 2024

Reference
https://www.nature.com/articles/s41467-024-47442-x

Confocal Live-Cell Imaging (Gene Expression)

Programmable RNA base editing with photoactivatable CRISPR-Cas13.

nature communications, January 2024

Reference
https://www.nature.com/articles/s41467-024-44867-2

Cytotoxicity_Drug screening for cardiac toxicity

Cardiotoxicity Assessment through a Polymer-Based Cantilever Platform:
An Integrated Electro-Mechanical Screening Approach.

Small, March 2024

Reference
https://onlinelibrary.wiley.com/doi/10.1002/smll.202311274

Cytosolic protein Localization

Quantitative control of subcellular protein localization with a photochromic dimerizer.

Nature Chemical Biology, June 2024

Reference
https://www.nature.com/articles/s41589-024-01654-w

Antibiotic Susceptibility

Full-Combinatorial Concentration Gradient Array with 3D Micro/Nanofluidics for Antibiotic Susceptibility Testing.

Analytical Chemistry, March 2024

Reference
https://pubs.acs.org/doi/10.1021/acs.analchem.3c05501

Cell viability Assay

Control of the signaling role of PtdIns(4)P at the plasma membrane through H2O2-dependent inactivation of synaptojanin 2 during endocytosis.

Redox Biology, May 2024

Reference
https://www.sciencedirect.com/science/article/pii/S2213231724000739?via%3Dihub

Cytotoxicity Assay

Enhancing cardiomyocytes contraction force measuring in drug testing: Integration of a highly sensitive single-crystal silicon strain sensor into SU-8 cantilevers.

Biosensors and Bioelectronics, January 2024

Reference
https://linkinghub.elsevier.com/retrieve/pii/S095656632300698X

Cytotoxicity Assay

Nano-chemical priming strategy to enhance TGF-β resistance and anti-tumor activity of natural killer cells.

Journal of Controlled Release, March 2024

Reference
https://www.sciencedirect.com/science/article/abs/pii/S0168365924000956?via%3Dihub