Applications

An extracellular, optogenetic antibody platform for stimulus-gated antigen recognition and modulation of cell behavior

FAM162A Is a Key Regulator of Mitochondrial Structure, Dynamics, and Bioenergetics, Driving Cellular Protection and Longevity

Microglial NLRP3-gasdermin D activation impairs blood-brain barrier integrity through interleukin-1β-independent neutrophil chemotaxis upon peripheral inflammation in mice

Remodeling synaptic connections via engineered neuron-astrocyte interactions

Distinct impact of PI(4)P flux on PI(4,5)P2 steady states and oscillations

Enhancing prestin oligomerization for superior sonogenetics

Optogenetic engineering of BAX to control mitochondrial permeabilization and attenuate apoptosis in cells

EGFR activation requires cholesterol interaction at the inner leaflet of the plasma membrane

One-day rapid sterility test for human-derived biopharmaceuticals

A Rho GTPase-effector ensemble governs cell migration behavior.

Locked Nucleic Acid-Modified Force Probe Reveals High-Force Regulation of Yes-Associated Protein through Talin–Vinculin in Breast Cancer

Imbalanced chromatin distribution in cellular senescence specifies paraspeckle dynamics

The membrane skeleton is constitutively remodeled in neurons by calcium signaling

ZSCAN4 functions as a safeguard to maintain centromere integrity during oocyte meiosis

SARS-CoV-2 uptake and inflammatory response in senescent endothelial cells are regulated by the BSG/VEGFR2 pathway.

Optogenetic storage and release of protein and mRNA in live cells and animals

Brain microenvironment-remodeling nanomedicine improves cerebral glucose metabolism,
mitochondrial activity and synaptic function in a mouse model of Alzheimer’s disease.

Hepatocyte TM4SF5-mediated cytosolic NCOA3 stabilization and macropinocytosis
support albumin uptake and bioenergetics for hepatocellular carcinoma progression.

Glutamylation of centrosomes ensures their function by recruiting microtubule
nucleation factors.

Boosting tumor homing of endogenous natural killer cells via therapeutic secretomes of chemically primed natural killer cells

ELK3-CYFIP2 axis-mediated actin remodeling modulates metastasis and natural killer cell responses in triple-negative breast cancer

Probiotic Antimicrobial Evaluation Via Real-Time Profiling of Bacterial Cell
Proliferation Using Stochastic Kinetics.

Super-photostable organic dye for long-term live-cell single-protein imaging.

Lipid Droplet Surface Promotes 3D Morphological Evolution of Non-Rhomboidal
Cholesterol Crystals.

Optogenetic calcium modulation in astrocytes enhances post-stroke recovery in
chronic capsular infarct.

Engineered Nanotopographies Induce Transient Openings in the Nuclear Membrane.

The Fanconi anemia core complex promotes CtIP-dependent end resection to drive
homologous recombination at DNA doublestrand breaks.

CRISPR-array-mediated imaging of non-repetitive and multiplex genomic loci in living cells.

Quantitative control of subcellular protein localization with a photochromic dimerizer.

Control of the signaling role of PtdIns(4)P at the plasma membrane through H2O2-dependent inactivation of synaptojanin 2 during endocytosis.

Optogenetic control of mRNA condensation reveals an intimate link
between condensate material properties and functions.

Full-Combinatorial Concentration Gradient Array with 3D Micro/Nanofluidics for Antibiotic Susceptibility Testing.

Cardiotoxicity Assessment through a Polymer-Based Cantilever Platform:
An Integrated Electro-Mechanical Screening Approach.

Nano-chemical priming strategy to enhance TGF-β resistance and anti-tumor activity of natural killer cells.

Real-time visualization of structural dynamics of synapses in live cells in vivo.

Programmable RNA base editing with photoactivatable CRISPR-Cas13.

Enhancing cardiomyocytes contraction force measuring in drug testing: Integration of a highly sensitive single-crystal silicon strain sensor into SU-8 cantilevers.