LED Irradiation

Optogenetical light stimulation(470nm)

Optogenetically Activatable MLKL as a Standalone Functional Module for Necroptosis and
Therapeutic Applications in Antitumoral Immunity.

Advanced Science, February 2025

Reference

https://advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202412393

Optogenetical light stimulation(475nm)

Optogenetic induction of TDP-43 aggregation impairs neuronal integrity
and behavior in Caenorhabditis elegans.

Translational Neurodegeneration, April 2025

Reference

https://translationalneurodegeneration.biomedcentral.com/articles/10.1186/s40035-025-00480-x

Full-field light illumination

Liquid-metal-based three-dimensional microelectrode arrays integrated with implantable ultrathin retinal prosthesis for vision restoration.

nature nanotechnology, January 2024

Reference

https://www.nature.com/articles/s41565-023-01587-w

Light stress inducing

A rapid inducible RNA decay system reveals fast mRNA decay in P-bodies.

nature communications, March 2024

Reference

https://www.nature.com/articles/s41467-024-46943-z

Light excitation for optogenetic purpose

Disruption of nuclear speckle integrity dysregulates RNA splicing in C9ORF72-FTD/ALS.

Neuron, October 2024

Reference

https://www.cell.com/neuron/abstract/S0896-6273(24)00570-1?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0896627324005701%3Fshowall%3Dtrue

Light excitation for optogenetic purpose

Phospholipase C beta 1 in the dentate gyrus gates fear memory formation through regulation of neuronal excitability.

Science Advances, Jul 2024

Reference

https://www.science.org/doi/10.1126/sciadv.adj4433

Time & intensity controlled light illumination

A single-component, light-assisted uncaging switch for endoproteolytic release.

nature chemical biology, November 2023

Reference

https://www.nature.com/articles/s41589-023-01480-6